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Warnings; Before taking; Dosage; Side effects; Interactions; What is Zestoretic? Zestoretic contains a combination of hydrochlorothiazide and lisinopril. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Lisinopril is in an ACE inhibitor. ACE enulose reviews Find patient medical information for Hydrochlorothiazide on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings The Lisinopril and Hydrochlorothiazide Tablets .5 mg combination worked equally well in black and white patients. The Lisinopril and Hydrochlorothiazide Tablets .5 mg and Lisinopril and Hydrochlorothiazide Tablets mg combinations appeared somewhat less effective in black patients, but relatively few black patients were studied.
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